Prep Guard Column Cartridge, RP C12, 10um, 100A. 21.2mm ID x 10mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C12 Guard Column Cartridges are packed with the same unique stationary phase used in Cogent RP C12 preparative columns. The adamantane-based bonded phase features a rigid, diamond-like carbon structure attached to high-purity silica with complete double endcapping. This distinctive chemistry provides excellent performance for complex mixtures, rapid equilibration between runs, and compatibility with 100% aqueous mobile phases while helping maintain the selectivity characteristics of RP C12 preparative columns.
68012-P21-PG1 is a preparative guard column cartridge packed with 10 µm RP C12 material featuring a 100 Å pore size in a 21.2 mm ID x 10 mm length stainless steel cartridge. Designed specifically for use with 21.2 mm ID preparative HPLC columns, this guard cartridge helps intercept particulates, strongly retained contaminants, and sample matrix components before they reach the main column. The matching stationary phase chemistry preserves chromatographic selectivity while protecting valuable preparative columns from contamination and premature fouling.
Used in preparative purification, fraction collection, and process development workflows, this guard cartridge helps preserve column efficiency, improve reproducibility, and reduce replacement costs. The stainless steel cartridge hardware and stainless steel frits provide durability for routine preparative chromatography operations and demanding purification applications.
Key Benefits
Packed with Cogent RP C12 stationary phase
Unique adamantane-based bonded phase
Fully double endcapped chemistry
High-purity silica support
Compatible with 100% aqueous mobile phases
Protects preparative HPLC columns from contaminants
Helps maintain column efficiency and reproducibility
Extends preparative column service life
Stainless steel cartridge construction
Stainless steel frits
Typical Applications
Preparative HPLC purification
Fraction collection
Compound isolation
Complex mixture purification
Process development
Method scale-up
Pharmaceutical research
Natural product purification
Synthetic chemistry
Preparative column protection
Specifications
Product Type: Preparative Guard Column Cartridge
Stationary Phase: RP C12
Chromatography Mode: Reversed Phase
Bonded Phase: Adamantane-Based C12 Ligand
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Cartridge Dimensions: 21.2 mm ID x 10 mm
Hardware Material: Stainless Steel
Frit Material: Stainless Steel
Quantity: 1 EA
Brand: Cogent
Guard Column Holder Requirement
A Cogent 21.2 mm ID Preparative Guard Column Holder is required for use with this guard cartridge.
View the Cogent 21.2 mm ID Preparative Guard Column Holder (83000-P21-GH)
Additional Resources
Important Notes
Compatible with Cogent RP C12 preparative HPLC columns
Compatible with 100% aqueous mobile phases
Designed to intercept particulates and contaminants before they reach the main column
Maintains RP C12 selectivity characteristics during purification
Recommended for routine purification and scale-up workflows
Replace as needed based on sample cleanliness and application requirements